COVID-19 early treatment: real-time analysis of 1,179 studies
Analysis of 30 COVID-19 early treatments, and database of 241 other potential treatments. 68 countries have approved early treatments. Treatments do not replace vaccines and other measures. All practical, effective, and safe means should be used. Elimination is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all variants. Denying efficacy increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage.
We aim to cover the most promising early treatments for COVID-19. We use pre-specified effect extraction criteria that prioritizes more serious outcomes, for details see methods. For specific outcomes and different treatment stages see the individual pages. Not all treatments are covered here, effectiveness has been reported for many other treatments in studies. Of the 1,179 studies, 780 present results comparing with a control group, 688 are treatment studies, and 92 analyse outcomes based on serum levels. There are 17 animal studies, 40 in silico studies, 58 in vitro studies, and 66 meta analyses.